药用微生物资源挖掘、生物制药

1. Chaolan Liu*, Ao Zhu, Jiabei Hou, Limei Wang, Ruilin Zhang, Jianghua Li, Yidong Guo, Yiwen Chu, “Nonomuraea sediminis sp. nov., a novel actinobacterium with antimicrobial activity, isolated from sediment of Dianchi Lake”, Archives of Microbiology 2023,205:91. doi:10.1007/s00203-023-03427-w.
2. Yidong Guo, Jianghua Li, Li Li, Chaolan Liu*, “Sphaerisporangium fuscum sp. nov., Isolated from Sediment of Anmucuo Lake in Tibet Autonomous Region of China”. Curr Microbiol 2022,79(12):362. doi: 10.1007/s00284-022-03067-1.
3. Chaolan Liu, Yidong Guo, Li Li, Jianghua Li, Limei Wang, Jiafu Lin, Xingrong Wang and Yiwen Chu*, “Acrocarpospora catenulata sp. nov., a novel actinobacterium isolated from lake sediment ”, Int. J. Syst. Evol. Microbiol. 2022,72:005526. doi: 10.1099/ijsem.0.005526.
4. Junjie Fu#, Chaolan Liu#, Li Li*, Jun Liu*, Yu Tie, et al., “Adaptive response and tolerance to weak acids in Saccharomyces cerevisiae boulardii: a metabolomics approach”, International Journal of Food Science and Technology 2022,57: 2918-2931.
5. Chaolan Liu, Yidong Guo, Li Li, Xiwei Wang, Jiafu Lin, Xingrong Wang, Jianghua Li and Yiwen Chu*, “Catellatospora sichuanensis sp. nov., a novel actinobacterium isolated from soil”, Int. J. Syst. Evol. Microbiol. 2020;70:3309–3315.
6. Chaolan Liu, Dan Huang and Wenxue Zhang*, “Combining culture-dependent and culture-independent molecular methods for the isolation and purification of a potentially novel anaerobic species from pit mud in a Chinese liquor distillery”, J.Inst. Brew. 2016, 122: 754-762.
7. Chaolan Liu, Haiying Wang, Zhengyun Wu, Wenxue Zhang* and Ao Fan, “Development of a real-time PCR for quantification of the family Syntrophomonadaceae in pit mud from Chinese Luzhou-flavour liquor distilleries”, J.Inst. Brew. 2015, 121: 155-162.
8. Chaolan Liu, Dan Huang, Laiyan Liu, Jin Zhang, Yu Deng, Ling Chen, Wenxue Zhang*, “Clostridium swellfunianum sp. nov., a novel anaerobic bacterium isolated from the pit mud of Chinese Luzhou-flavor liquor production”, Antonie van Leeuwenhoek 2014,106:817-825.
9. 刘超兰, 黎江华, 郭义东*. 2株小双孢菌新种的全基因组测序分析与抗菌活性测定, 微生物学通报, 2021,48(5):1662-1673.
10. 潘文娟, 林家富, 王小桃, 郭义东, 褚以文, 刘超兰*. 西藏湖泊放线菌的分离鉴定及抗菌活性测定, 生物技术通报, 2020, 36(7): 8-14.

纵向课题：
1. 主持四川省科技厅应用基础项目:《西南地区湖泊放线菌资源勘探和新结构活性次级代谢产物挖掘》，2020YJ0276, 2020-2022
2. 主持抗生素研究与再评价四川省重点实验室开放课题：《土壤小双孢菌的选择性分离、抗菌活性与功能基因研究》，ARRLKF15-02，2016-2018
3. 主持成都大学青年校基金项目：《两株小双孢菌潜在新种的多相分类及生物活性物质合成基因研究》，2080516013, 2016-2018
4. 主持成都大学引进人才启动项目：《特殊生境稀有放线菌筛选与生物活性物质》，2081915049，2015-2020.
5. 作为骨干成员参与科技部科技基础工作专项：《中国湖泊微生物多样性及资源调查》，2017FY100300，2017-2022.
6. 作为骨干成员参与四川省科技厅基础条件平台建设专项：《四川省医药微生物共享服务平台建设》，15010302，2015-2017.
授权专利：
1. 高效分离纯化纽莫康定的方法。2019,中国专利ZL201610232761.9