师资队伍

彭西

职称:教授

最高学历毕业院校及专业:四川农业大学 预防兽医学

所属学科:药理学

电子邮件:pengxi@cdu.edu.cn

个人简历

研究方向

代表性论著

教学科研项目及获奖

职称 教授 最高学历毕业院校及专业 四川农业大学 预防兽医学
所属学科 药理学 电子邮箱 pengxi@cdu.edu.cn
研究方向 药毒和药效评价。评价各种化药、中药单体及中药复方的安全性,确定毒性靶器官,并研究毒性机制。主要用溃疡性结肠炎和慢性阻塞性肺炎模型筛选药物,评价药效并研究治疗机制。 发表论文 1.Peng, Xi(第一作者),Yang, Yinxiang, Zhong, Rao. Zinc and Inflammatory Bowel Disease: from clinical study to animal experiment Biol. Trace Elem. Res. 2024<br>
2.Changlin Wen, Dan Chen, Rao Zhong, Xi Peng(通讯作者).Animal models of inflammatory bowel disease: category and evaluation indexes. Gastroenterology Report. 2024, https://doi.org/10.1093/gastro/goae021.<br>
3.Changlin Wen, Zhengqiang Yu, Juan Wang, Qing Deng, Jiajia Deng, Zhenhua Sun, Qiaobo Ye, Kaihua Qin, Xi Peng(通讯作者). Inhalation of Citrus Reticulata essential oil alleviates airway inflammation and emphysema in COPD rats through regulation of macrophages. Journal of Ethnopharmacology. 2023, https://doi.jep.2023.117407.<br>
4.Changlin Wen, Jiayu Wang, Zhenhua Sun, Rao Zhong, Mengjie Li, Xuemei Shen,Qiaobo Ye, Kaihua Qin, Xi Peng(通讯作者). Dietary zinc ameliorates TNBS-induced colitis in mice associated with regulation of regulation of Th1/Th2/Th17 balance and NF-кB/NLRP3 signaling pathway. Bilogical Trace Element Research. 2023, 5: https://doi.org/10.1007/s12011-023-03715-y.<br>
5.Lin Chen, Tong Cai, Cuiyan Zhao, Shiping Bai, Gang Shu, Changlin Wen, Qinkun Xu, and Xi Peng(通讯作者). Atmospheric  ammonia causes histopathological lesions, cell cycle blockage, and apoptosis of spleen in chickens. Canadian Journal of Animal Science. 2022, 102: 448-456. 10.1139/cjas-2021-0084<br>
6.Shiping Bai, Xi Peng, Caimei Wu, Tong Cai, Jiangfeng Liu and Gang Shu. Effects of dietary inclusion of Radix Bupleuri extract on the growth performance, and ultrastructural changes and apoptosis of lung epithelial cells in broilers exposed to atmospheric ammonia. Journal of Animal Science, 2021, 99, No. 11, 1-13. https://doi.org/10.1093/jas/skab313<br>
7.Bangyuan Wu, Zhengqiang Yu, Jiajia Deng, Shibin Yuan, Xi Peng. Histomorphological structure of the bursa cloacalis in young leiothrix lutea: a comparative study using light microcopy and transmission electron microscopy. Int. J. Morphol. 2021, 39(4):977-985.<br>
8.Bangyuan Wu, Muhammad Jameel Mughalc, Jing Fang, Xi Peng. The protective role of selenium against AFB1 induced liver apoptosis by death receptor pathway in broilers. Biological Trace Element Research. 2019, 191: 453-463<br>
9.Jing Fang, Panpan Zhu, Zhuangzhi Yang, Xi Peng et al. Selenium Ameliorates AFB1−Induced Excess Apoptosis in Chicken Splenocytes Through Death Receptor and Endoplasmic Reticulum Pathways. Biological Trace Element Research. 2019, 187: 273-280. https://doi.org/10.1007/s12011-018-1361-7<br>
10.Ke Guan1,2 & Hang Li1,2 & Zhicai Zuo1,2 & Fengyuan Wang1,2 & Ping Hu1,2 & Xi Peng3 & Jing Fang1,2. The molecular mechanisms of protective role of Se on the G0/G1 phase arrest caused by AFB1 in broiler’s thymcytes. Biological Trace Element Research. 2018, https://doi.org/10.1007/s12011-018-1491-y<br>
11.Fengyuan Wang, Zhicai Zuo, Kejie Chen, Caixia Gao, zhuangzhi Yang, Song Zhao, Jianzhen Li, Hetao Song, Xi Peng, Jing Fang et al. Histopathological injuries, ultrastructural changes, and depressed TLR expression in the small intestine of broiler chickens with aflatoxin B1. Toxins. 2018, 10(4), 131; doi:10. 3390/toxins10040131<br>
12.Ke Guan, Hang Li, Zhicai Zuo, Fengyuan Wang, Ping Hu, Xi Peng, Jing Fang. The molecular mechanisms of protective role of Se on the G0/G1 phase arrest caused by AFB1 in broiler’s thymocytes. Biological Trace Element Research. 2019, 189: 556-566. https://doi.org/10.1007/s12011-018-1412-0<br>
13.Jing Fang, Zhixiang Zheng, Zhuangzhi Yang, Xi Peng, Zhicai Zuo, et al. Ameliorative effects of selenium on the excess apoptosis of the jejunum caused by AFB1 through death receptor and endoplasmic reticulum pathways. Toxicology Research. 2018, 7(6): 1108-1119. doi:10.1039/ c8tx00068a<br>
14.Ping Hu, Zhicai Zuo, Fengyuan Wang, Xi Peng, et al. The protective role of selenium in AFB1-induced tissue damage and cell cycle arrest in chicken’s bursa of fabricius. Biological Trace Element Research. 2018, 185(2): 486-496. https://doi.org/ 10.1007/s12011-018-1273-6
15.Xi Peng, Shiping Bai, Xuemei Ding, Keying Zhang. Pathological Impairment, Cell Cycle Arrest and Apoptosis of Thymus and Bursa of Fabricius Induced by Aflatoxin-contaminated Corn in Broilers. IJERPH, 2017, 14(1), 77; doi:10.3390/ijerph14010077<br>
16.Muhammad Jameel Mughal, Xi Peng(通讯作者), Yi Zhou, Jing Fang. Aflatoxin B1 invokes apoptosis via death receptor pathway in hepatocytes. Oncotarget, 2017, 8(5):8239-8249. Doi: 10.18632/oncotarget.14158.<br>
17.Muhammad Jameel Mughal, Xi Peng(通讯作者), Asghar Ali Kamboh, Yi Zhou, Jing Fang. Aflatoxin B1 Induced Systemic Toxicity in Poultry and Rescue Effects of Selenium and Zinc. Biol Trace Elem Res, 2017, 178(2): 292-300. DOI 10.1007/s12011-016-0923-9.<br>
18.CH Wang,X Peng,HM Cui,J Fang. Effects of aflatoxin B1 on the erythrocyte count, the content of hemoglobin, and the immune adherence function of erythrocytes in chickens. 《Medycyna Weterynaryjna》, 2015, 71(12):758-762.<br>
19.Shibin Yuan, Bangyuan Wu, Zhengqiang Yu, Jing Fang, Na Liang, Mingqiang Zhou, Cheng Huang, Xi Peng. The mitochondrial and endoplasmic reticulum pathways involved in the apoptosis of bursa of Fabricius cells in broilers exposed to dietary aflatoxin B1[J]. Oncotarget, 2016, 7(40): 65295-65306. DOI: 10.18632/oncotarget.11321.<br>
20.Xi Peng, Zhengqiang Yu, Na Liang, et al. The mitochondrial and death receptor pathways involved in the thymocytes apoptosis induced by aflatoxin B1.[J]. Oncotarget, 2016, 7(11): 12222-12234.(SCI收录)<br>
Xi Peng, Kejie Chen, Jin Chen, Jing Fang, Hengmin Cui, Zhicai Zuo, Junliang Deng, Zhengli Chen, Yi Geng and Weimin Lai. Aflatoxin B1 affects apoptosis and expression of Bax, Bcl-2, and Caspase-3 in thymus and bursa of fabricius in broiler chickens[J]. Environmental Toxicology, 2016, 31(9):1113-1120.(SCI收录)<br>
教学科研成果 一、专利<br>
1. 王佳瑜;彭西;温昌琳等. 一种肠道瑞士卷制作装置,2023-3-24专 利 号:ZL 2022 2 2289318.9<br>
2. 彭西;温昌琳; 一种实验动物熏烟COPD造模系统装置, 2021-12-24, 中国, ZL 2021 2 1262643.5 <br>
3. 彭西; 张泽钧; 袁施彬; 吴邦元; 流式细胞术检测鸡胸腺T淋巴细胞亚群的方法, 2020-11-06, 中国, ZL 2017 1 0324078.2 <br>
二、科研项目<br>
主持,国家林业局项目,圈养大熊猫病理学诊断体系的构建,2017-2019,20万;<br>
主持,成都大学引进人才项目,DSS自由饮法和TNBS灌肠法建立大小鼠溃疡性结肠模型及药物筛选初探,2019-2024,100万。<br>
主持,四川省高新区创业类项目,金熊猫人才项目,2019-2022,50万<br>
主研,国家自然科学基金,透脓散诱导线粒体自噬调控NF-KB/NLRP3信号通路抗溃疡性结肠炎的机制研究(81973742),2019-2023,55万。<br>
三、出版著作<br>
1. 副主编《兽医病理解剖学》,中国农业出版社,2018,ISBN:978-7-109-23817-6<br>
2. 副主编《动物营养代谢疾病诊断病理学》,中国农业出版社,2011,ISBN:9787109151284<br>
3. 编译《默克兽医手册第十版》,中国农业出版社,2015,978-7-109-20750-9<br>

彭西,博士研究生,教授。中国畜牧兽医学会高级会员,中国兽医病理学会会员,四川扬克斯特科技有限公司首席顾问。

最高学历毕业院校及专业:2009年6月毕业于四川农业大学预防兽医学专业

所属学科:药理学

研究方向:药毒和药效评价。评价各种化药、中药单体及中药复方的安全性,确定毒性靶器官,并研究毒性机制。主要用溃疡性结肠炎和慢性阻塞性肺炎模型筛选药物,评价药效并研究治疗机制。

海外学习经历:2010年9月至10月受国家林业局委派,在日本神户市王子动物园执行国家公务及短期学习。

获奖或荣誉称号:四川省学术与技术带头人后备人选

电子邮件:pengxi@cdu.edu.cn

药毒和药效评价。评价各种化药、中药单体及中药复方的安全性,确定毒性靶器官,并研究毒性机制。主要用溃疡性结肠炎和慢性阻塞性肺炎模型筛选药物,评价药效并研究治疗机制。

1.Peng, Xi(第一作者),Yang, Yinxiang, Zhong, Rao. Zinc and Inflammatory Bowel Disease: from clinical study to animal experiment Biol. Trace Elem. Res. 2024
2.Changlin Wen, Dan Chen, Rao Zhong, Xi Peng(通讯作者).Animal models of inflammatory bowel disease: category and evaluation indexes. Gastroenterology Report. 2024, https://doi.org/10.1093/gastro/goae021.
3.Changlin Wen, Zhengqiang Yu, Juan Wang, Qing Deng, Jiajia Deng, Zhenhua Sun, Qiaobo Ye, Kaihua Qin, Xi Peng(通讯作者). Inhalation of Citrus Reticulata essential oil alleviates airway inflammation and emphysema in COPD rats through regulation of macrophages. Journal of Ethnopharmacology. 2023, https://doi.jep.2023.117407.
4.Changlin Wen, Jiayu Wang, Zhenhua Sun, Rao Zhong, Mengjie Li, Xuemei Shen,Qiaobo Ye, Kaihua Qin, Xi Peng(通讯作者). Dietary zinc ameliorates TNBS-induced colitis in mice associated with regulation of regulation of Th1/Th2/Th17 balance and NF-кB/NLRP3 signaling pathway. Bilogical Trace Element Research. 2023, 5: https://doi.org/10.1007/s12011-023-03715-y.
5.Lin Chen, Tong Cai, Cuiyan Zhao, Shiping Bai, Gang Shu, Changlin Wen, Qinkun Xu, and Xi Peng(通讯作者). Atmospheric ammonia causes histopathological lesions, cell cycle blockage, and apoptosis of spleen in chickens. Canadian Journal of Animal Science. 2022, 102: 448-456. 10.1139/cjas-2021-0084
6.Shiping Bai, Xi Peng, Caimei Wu, Tong Cai, Jiangfeng Liu and Gang Shu. Effects of dietary inclusion of Radix Bupleuri extract on the growth performance, and ultrastructural changes and apoptosis of lung epithelial cells in broilers exposed to atmospheric ammonia. Journal of Animal Science, 2021, 99, No. 11, 1-13. https://doi.org/10.1093/jas/skab313
7.Bangyuan Wu, Zhengqiang Yu, Jiajia Deng, Shibin Yuan, Xi Peng. Histomorphological structure of the bursa cloacalis in young leiothrix lutea: a comparative study using light microcopy and transmission electron microscopy. Int. J. Morphol. 2021, 39(4):977-985.
8.Bangyuan Wu, Muhammad Jameel Mughalc, Jing Fang, Xi Peng. The protective role of selenium against AFB1 induced liver apoptosis by death receptor pathway in broilers. Biological Trace Element Research. 2019, 191: 453-463
9.Jing Fang, Panpan Zhu, Zhuangzhi Yang, Xi Peng et al. Selenium Ameliorates AFB1−Induced Excess Apoptosis in Chicken Splenocytes Through Death Receptor and Endoplasmic Reticulum Pathways. Biological Trace Element Research. 2019, 187: 273-280. https://doi.org/10.1007/s12011-018-1361-7
10.Ke Guan1,2 & Hang Li1,2 & Zhicai Zuo1,2 & Fengyuan Wang1,2 & Ping Hu1,2 & Xi Peng3 & Jing Fang1,2. The molecular mechanisms of protective role of Se on the G0/G1 phase arrest caused by AFB1 in broiler’s thymcytes. Biological Trace Element Research. 2018, https://doi.org/10.1007/s12011-018-1491-y
11.Fengyuan Wang, Zhicai Zuo, Kejie Chen, Caixia Gao, zhuangzhi Yang, Song Zhao, Jianzhen Li, Hetao Song, Xi Peng, Jing Fang et al. Histopathological injuries, ultrastructural changes, and depressed TLR expression in the small intestine of broiler chickens with aflatoxin B1. Toxins. 2018, 10(4), 131; doi:10. 3390/toxins10040131
12.Ke Guan, Hang Li, Zhicai Zuo, Fengyuan Wang, Ping Hu, Xi Peng, Jing Fang. The molecular mechanisms of protective role of Se on the G0/G1 phase arrest caused by AFB1 in broiler’s thymocytes. Biological Trace Element Research. 2019, 189: 556-566. https://doi.org/10.1007/s12011-018-1412-0
13.Jing Fang, Zhixiang Zheng, Zhuangzhi Yang, Xi Peng, Zhicai Zuo, et al. Ameliorative effects of selenium on the excess apoptosis of the jejunum caused by AFB1 through death receptor and endoplasmic reticulum pathways. Toxicology Research. 2018, 7(6): 1108-1119. doi:10.1039/ c8tx00068a
14.Ping Hu, Zhicai Zuo, Fengyuan Wang, Xi Peng, et al. The protective role of selenium in AFB1-induced tissue damage and cell cycle arrest in chicken’s bursa of fabricius. Biological Trace Element Research. 2018, 185(2): 486-496. https://doi.org/ 10.1007/s12011-018-1273-6 15.Xi Peng, Shiping Bai, Xuemei Ding, Keying Zhang. Pathological Impairment, Cell Cycle Arrest and Apoptosis of Thymus and Bursa of Fabricius Induced by Aflatoxin-contaminated Corn in Broilers. IJERPH, 2017, 14(1), 77; doi:10.3390/ijerph14010077
16.Muhammad Jameel Mughal, Xi Peng(通讯作者), Yi Zhou, Jing Fang. Aflatoxin B1 invokes apoptosis via death receptor pathway in hepatocytes. Oncotarget, 2017, 8(5):8239-8249. Doi: 10.18632/oncotarget.14158.
17.Muhammad Jameel Mughal, Xi Peng(通讯作者), Asghar Ali Kamboh, Yi Zhou, Jing Fang. Aflatoxin B1 Induced Systemic Toxicity in Poultry and Rescue Effects of Selenium and Zinc. Biol Trace Elem Res, 2017, 178(2): 292-300. DOI 10.1007/s12011-016-0923-9.
18.CH Wang,X Peng,HM Cui,J Fang. Effects of aflatoxin B1 on the erythrocyte count, the content of hemoglobin, and the immune adherence function of erythrocytes in chickens. 《Medycyna Weterynaryjna》, 2015, 71(12):758-762.
19.Shibin Yuan, Bangyuan Wu, Zhengqiang Yu, Jing Fang, Na Liang, Mingqiang Zhou, Cheng Huang, Xi Peng. The mitochondrial and endoplasmic reticulum pathways involved in the apoptosis of bursa of Fabricius cells in broilers exposed to dietary aflatoxin B1[J]. Oncotarget, 2016, 7(40): 65295-65306. DOI: 10.18632/oncotarget.11321.
20.Xi Peng, Zhengqiang Yu, Na Liang, et al. The mitochondrial and death receptor pathways involved in the thymocytes apoptosis induced by aflatoxin B1.[J]. Oncotarget, 2016, 7(11): 12222-12234.(SCI收录)
Xi Peng, Kejie Chen, Jin Chen, Jing Fang, Hengmin Cui, Zhicai Zuo, Junliang Deng, Zhengli Chen, Yi Geng and Weimin Lai. Aflatoxin B1 affects apoptosis and expression of Bax, Bcl-2, and Caspase-3 in thymus and bursa of fabricius in broiler chickens[J]. Environmental Toxicology, 2016, 31(9):1113-1120.(SCI收录)

一、专利
1. 王佳瑜;彭西;温昌琳等. 一种肠道瑞士卷制作装置,2023-3-24专 利 号:ZL 2022 2 2289318.9
2. 彭西;温昌琳; 一种实验动物熏烟COPD造模系统装置, 2021-12-24, 中国, ZL 2021 2 1262643.5
3. 彭西; 张泽钧; 袁施彬; 吴邦元; 流式细胞术检测鸡胸腺T淋巴细胞亚群的方法, 2020-11-06, 中国, ZL 2017 1 0324078.2
二、科研项目
主持,国家林业局项目,圈养大熊猫病理学诊断体系的构建,2017-2019,20万;
主持,成都大学引进人才项目,DSS自由饮法和TNBS灌肠法建立大小鼠溃疡性结肠模型及药物筛选初探,2019-2024,100万。
主持,四川省高新区创业类项目,金熊猫人才项目,2019-2022,50万
主研,国家自然科学基金,透脓散诱导线粒体自噬调控NF-KB/NLRP3信号通路抗溃疡性结肠炎的机制研究(81973742),2019-2023,55万。
三、出版著作
1. 副主编《兽医病理解剖学》,中国农业出版社,2018,ISBN:978-7-109-23817-6
2. 副主编《动物营养代谢疾病诊断病理学》,中国农业出版社,2011,ISBN:9787109151284
3. 编译《默克兽医手册第十版》,中国农业出版社,2015,978-7-109-20750-9