1.抗肿瘤及抗菌光疗药物的研发及应用；
2.荧光探针的开发及其生物医学检测应用；
3.高性能荧光染料的设计合成及超分辨成像应用。

[1] Ren Xiaojie, Wang Chao, Wu Xia, Rong Mengtao, Huang Rong, Liang Qin, Shen Tianruo, Sun Hongyan, Zhang Ruilong,* Zhang Zhongping, Liu Xiaogang,* Song Xiangzhi,* Foley James W. Auxochrome dimethyl-dihydroacridine improves fluorophores for prolonged live-cell super-resolution imaging. Journal of the American Chemical Society, 146(2024) 6566−6579.
[2] Ren Xiaojie, Li Haokun, Peng Hui, Yang Yang, Su Hang, Huang Chen, Xuan Wang, Zhang Jie, Liu Zhiyang, Wei Wenyu, Cheng Ke, Lu Zhenpin, Li Zhengqiu, Zhao Qian, Tang Benzhong, Yao Shao Q.,* Song Xiangzhi,* Sun Hongyan.* Reactivity-tunable fluorescent platform for selective and biocompatible modification of cysteine or lysine. Advanced Science, (2024) e2402838.
[3] Ren Xiaojie, Yang Sheng, Wang Benhua, Yao Chaoyi, Liu Qing,* Song Xiangzhi.* Dimethyl dihydro-phenazine: a highly conjugated auxochrome in fluorophores to improve photostability, red-shift wavelength and enlarge Stokes shift. Analytical Chemistry, 96(2024) 10416–10425.
[4] Ren Xiaojie,† Han Shaohui,† Li Yiling, Zeng Yuyang, Li Haipu, Yao Chaoyi, Yang Lei,* Song Xiangzhi.* Tumor microenvironment-activatable phototheragnostic: leveraging nitric oxide and weak acidity as dual biomarkers for ratiometric fluorescence, photoacoustic imaging, and photothermal therapy. Analytical Chemistry, 96(2024) 8689–8695.
[5] Han Shaohui, Zeng Yuyang, Li Yiling, Li Haipu, Yang Lei, Ren Xiaojie,* Lan Minhuan,* Wang Benhua, Song Xiangzhi.* Carbon Monoxide: A second biomarker to couple with viscosity for the construction of "dual-locked" near-infrared fluorescent probes for accurately diagnosing non-alcoholic fatty liver disease, Analytical Chemistry, 95(2023) 18619-18628.
[6] Yang Yitong, Zhong Hao, Wang Benhua, Ren Xiaojie,* Song Xiangzhi.* Coumarin-based two-photon AIE fluorophores: Photophysical properties and biological application, Chinese Chemical Letters, 34(2023) 107674.
[7] Ren Xiaojie,† Liao Lide,† Yang Zhaoguang, Li Haipu, Li Xi, Wang Yangang,* Ye Yong, Song Xiangzhi.* Rational design of a bifunctional fluorescent probe for distinguishing Hcy/Cys from GSH with ideal properties, Chinese Chemical Letters, 32(2021) 1061-1065.
[8] Huang Chen,† Ren Xiaojie,† Chen Qingxin,† Zhang Jie,* Gan Shenglong, Jiang Yin,* Yang Liu,* Sun Hongyan.* A novel NIR-activatable and photodegradable mitochondria-targeted nano-photosensitizer for superior photodynamic therapy, Sensors and Actuators B: Chemical, 424(2025) 136896.
[9] Ren Xiaojie,† Zhang Fan,† Luo Hongchen, Liao Lide, Song Xiangzhi,* Chen Wenqiang.* Red-emitting boron difluoride complexes with a mega-large Stokes shift and unexpectedly high fluorescence quantum yield, Chemical Communications, 56(2020) 2159-2162.
[10] Ren Xiaojie,† Zhang Yun,† Zhang Fan, Zhong Hao, Wang Jingpei, Liu Xingjiang,* Yang Zhaoguang, Song Xiangzhi.* Red-emitting fluorescent probe for discrimination of Cys/Hcy and GSH with a large Stokes shift under a single-wavelength excitation, Analytica Chimica Acta, 1097(2020) 245-253.
[11] Niu Peixin, Tian Rumeng, Liu Zengrong, Ran Jie, Liu Jiaojiao, Li Yuhan, Ren Xiaojie,* Liu Xingjiang,* Wei Liuhe. Red/near-infrared chromenoquinoline dyes for LEDs and mitochondria labeling, Dyes and Pigments, 205(2022) 110485.
[12] Tian Rumen,† Ren Xiaojie,† Niu Peixin, Yang Lei,* Sun Ailing, Li Yuhan, Liu Xingjiang,* Wei Liuhe. Development of chromenoquinoline-fused coumarin dyes and their application in bioimaging, Dyes and Pigments, 205(2022) 110530.
[13] Ren Xiaojie, Guo Man, Gong Junyi, Zhang Yun, Yang Lei, Liu Xingjiang,* Song Xiangzhi.* Construction of red-emitting iminocoumarin-based fluorescent borate complexes with a large Stokes shift, Dyes and Pigments, 173(2020) 108007.
[14] Liang Qin, Chen Wenqiang, Ren Xiaojie,* Song Xiangzhi.* Red-emitting rhodamine-based probe with large Stokes shift for ClO-detection, Tetrahedron, 127(2022) 133020.
[15] Shangguan Huiming, Teng Zixuan, Ren Xiaojie,* Liu Xingjiang.* Harnessing J-aggregation for dual-color cellular imaging with chromenoquinoline-benzimidazole dyes, Organic & Biomolecular Chemistry, 22(2024) 7173-7179.
[16] Ren Xiaojie, Tian Huihui, Yang Lei, He Long, Geng Yani, Liu Xingjiang,* Song Xiangzhi.* Fluorescent probe for simultaneous discrimination of Cys/Hcy and GSH in pure aqueous media with a fast response under a single-wavelength excitation, Sensors and Actuators B: Chemical, 273(2018) 1170-1178.

近五年，以第一/通讯作者在J. Am. Chem. Soc., Adv. Sci., Anal. Chem., Chem. Commun.等国际知名学术期刊发表SCI论文15篇。曾获得“国家奖学金”，“校长拔尖奖学金”，“互联网+创新创业大赛全国银奖”等多项荣誉。