1.Fei Zhao, Ariane Mattana, Ruqaiya Alam, Sarah Montgomery, Akash Pandya, Fabrizio Manetti, Beatriz Dominguez,* Daniele Castagnolo.* Cooperative chemoenzymatic and biocatalytic cascades to access chiral sulfur compounds bearing C(sp3)–S stereocentres. Nat. Commun. 2024, 15, 8332.
2.Xin Gong,# Na Yu,# Linghui Gu, Zheyu Li,* Wenbo Ma,* Fei Zhao.* Redox-Neutral Rhodium(III)-Catalyzed Divergent Synthesis of Tetrasubstituted 1,3-Enynes and Alkynylated Benzofurans. Org. Biomol. Chem. 2023, 21, 147–152.
3.Fei Zhao, Kate Lauder, Siyu Liu, James D. Finnigan, Simon B. R. Charnock, Simon J. Charnock, Daniele Castagnolo.* Chemoenzymatic Cascades for the Enantioselective Synthesis of β-Hydroxysulfides Bearing a Stereocentre at the C−O or C−S Bond by Ketoreductases. Angew. Chem. Int. Ed. 2022, e202202363.
4.Hui Mao,* Jing Chen, Xiaoning Zhang, Na Yu, Yangbin Lu,* Fei Zhao.* Regio- and Stereoselective Synthesis of Tetrasubstituted Alkenes via Ruthenium(II)-Catalyzed C–H Alkenylation/Directing Group Migration. ChemistrySelect 2022, 7, e20220029.
5.Fei Zhao,*,# Zhi Zhou,# Yangbin Lu,# Jin Qiao, Xiaoning Zhang, Xin Gong, Siyu Liu, Shuang Lin, Xiaowei Wu,* Wei Yi.* Chemo-, Regio-, and Stereoselective Assembly of Polysubstituted Furan-2(5H)-ones Enabled by Rh(III)-Catalyzed Domino C–H Alkenylation/Directing Group Migration/Lactonization: A Combined Experimental and Computational Study. ACS Catal. 2021, 11, 13921–13934.
6.Fei Zhao,* Jin Qiao, Yangbin Lu, Xiaoning Zhang, Long Dai, Xin Gong, Hui Mao,* Shiyao Lu, Xiaowei Wu, Siyu Liu.* Rh(III)-Catalyzed Divergent Synthesis of Alkynylated Imidazo[1,5-a]indoles and α,α-Difluoromethylene Tetrasubstituted Alkenes. Org. Lett. 2021, 23, 5766–5771.
7.Fei Zhao,* Xin Gong, Yangbin Lu, Jin Qiao, Xiuwen Jia, Hangcheng Ni, Xiaowei Wu,* Xiaoning Zhang.* Additive-Controlled Divergent Synthesis of Tetrasubstituted 1,3-Enynes and Alkynylated 3H-Pyrrolo[1,2-a]indol-3-ones via Rhodium Catalysis. Org. Lett. 2021, 23, 727–733.
8.Fei Zhao,*,# Jing Chen,# Jin Qiao, Yangbin Lu, Xiaoning Zhang, Hui Mao,* Shiyao Lu, Xin Gong, Siyu Liu, Xiaowei Wu, Long Dai.* Chemo-and Regioselective Synthesis of Functionalized 1H-imidazo[1,5-a]indol-3(2H)-ones via a Redox-Neutral Rhodium(III)-Catalyzed [4+1] Annulation between Indoles and Alkynes. Adv. Synth. Catal. 2021, 363, 4380–4389.
9.Fei Zhao,* Jin Qiao, Yangbin Lu, Xiaoning Zhang, Long Dai, Siyu Liu, Hangcheng Ni,* Xiuwen Jia, Xiaowei Wu, Shiyao Lu.* Redox-Neutral Rhodium(III)-Catalyzed Chemospecific and Regiospecific [4+1] Annulation between Indoles and Alkenes for the Synthesis of Functionalized Imidazo[1,5-a]indoles. J. Org. Chem. 2021, 86, 10591–10607.
10.Hangcheng Ni,* Yu Li, Xingzi Shi, Yi Pang, Congying Jin, Fei Zhao.* Eosin Y as a Direct Hydrogen-Atom Transfer Photocatalyst for the C3–H Acylation of Quinoxalin-2(1H)-ones. Tetrahedron Lett. 2021, 68, 152915.
11.Siyu Liu,# Hui Mao,# Jin Qiao,# Xiaoning Zhang, Yangbin Lu, Xin Gong, Aiqiong Jia, Linghui Gu,* Xiaowei Wu,* Fei Zhao.* Temperature-Controlled Divergent Synthesis of Tetrasubstituted Alkenes and Pyrrolo[1,2-a]indole Derivatives via Iridium Catalysis. Asian J. Org. Chem. 2021, 10, 3308–3320.
12.Xiaowei Wu, Yangbin Lu, Jin Qiao, Wenhao Dai, Xiuwen Jia, Hangcheng Ni, Xiaoning Zhang,* Hong Liu,* Fei Zhao.* Rhodium(III)-Catalyzed C–H Alkenylation/Directing Group Migration for the Regio- and Stereoselective Synthesis of Tetrasubstituted Alkenes. Org. Lett. 2020, 22, 9163–9168.
13.Xiaowei Wu#, Pinyi Li#, Yangbin Lu, Jin Qiao, Jingwei Zhao,* Xiuwen Jia, Hangcheng Ni, Lichun Kong, Xiaoning Zhang,* Fei Zhao.* Rhodium-Catalyzed Cascade Reactions of Indoles with 4-Hydroxy-2-Alkynoates for the Synthesis of Indole-Fused Polyheterocycles. Adv. Synth. Catal. 2020, 362, 2953–2960.
14.Xiuwen Jia#, Pinyi Li#, Xiaoning Zhang, Siyu Liu, Xingzi Shi, Wenbo Ma, Hongbo Dong, Yangbin Lu,* Hangcheng Ni,* Fei Zhao.* Metal-Free Selective and Diverse Synthesis of Three Distinct Sets of Isoindolinones from 2-Alkynylbenzoic Acids and Amines. Eur. J. Org. Chem. 2020, 7343–7357.
15.Hangcheng Ni,* Xingzi Shi, Yu Li, Xiaoning Zhang, Jingwei Zhao,* Fei Zhao.* Metal-Free C3–H Acylation of Quinoxalin-2(1H)-ones with α-Oxo-Carboxylic acids. Org. Biomol. Chem. 2020, 18, 6558–6563.
16.Pinyi Li,# Xiuwen Jia,# Xiaoli Ma, Wenbo Ma, Yilin Sheng, Jingwei Zhao,* Fei Zhao.* A Catalyst-Free Cascade Reaction for the Selective Assembly of 3-Hydroxyisoindolinones on Water. Asian J. Org. Chem. 2019, 8, 2073–2091.
17.Xiuwen Jia, Pinyi Li, Xiaoyan Liu, Jiafu Lin,* Yiwen Chu, Jinhai Yu, Jiang Wang, Hong Liu,* Fei Zhao.* Green and Facile Assembly of Diverse Fused N-Heterocycles Using Gold-Catalyzed Cascade Reactions in Water. Molecules 2019, 24, 988.
18.Fei Zhao, Xiuwen Jia, Pinyi Li, Jingwei Zhao, Yu Zhou, Jiang Wang, Hong Liu.* Catalytic and Catalyst-Free Diboration of Alkynes. Org. Chem. Front. 2017, 4, 2235–2255.
19.Fei Zhao,* Xiuwen Jia, Jingwei Zhao, Chaoli Fei, Liyang Liu, Guannan Liu, Dongping Wang, Fei Chen. Palladium(II)-Catalyzed ortho-C–H Olefination of Phenylalanine and Phenylethylamine Derivatives Directed by Removable Picolinamide Group. RSC Adv. 2017, 7, 25031–25040.
20.Fei Zhao,# Jing Li,# Ying Chen, Yanxin Tian, Chenglin Wu, Yanan Xie, Yu Zhou, Jiang Wang, Xin Xie,* Hong Liu.* Design, Synthesis and Biological Evaluation of Indoline and Indole Derivatives as Potent and Selective α1A-Adrenoceptor Antagonists. J. Med. Chem. 2016, 59, 3826–3839.
21.Chenglin Wu,# Fei Zhao,# Yonglei Du, Liang Zhao, Liang Chen, Jiang Wang, Hong Liu.* Highly Selective Intramolecular Addition of C–N and S–N Bonds to Alkynes Catalyzed by Palladium: a Practical Access to Two Distinct Functional Indoles. RSC Adv. 2016, 6, 70682–70690.
22.Chenglin Wu,# Fei Zhao,# Shuangjie Shu, Jiang Wang, Hong Liu.* Palladium-Catalyzed Intramolecular Addition of C–N Bond to Alkynes: a Novel Approach to 3-Diketoindoles. RSC Adv. 2015, 5, 90396–90399.
23.Fei Zhao,# Dengyou Zhang,# Yong Nian, Lei Zhang, Wei Yang, Hong Liu.* Palladium-Catalyzed Difunctionalization of Alkynes via C–N and S–N Cleavages: a Versatile Approach to Highly Functional Indoles. Org. Lett. 2014, 16, 5124–5127.
24.Fei Zhao, Lei Zhang, Hailong Liu, Shengbin Zhou, Hong Liu.* Microwave-Assisted Synthesis of 5,6-Dihydroindolo[1,2-a]quinoxaline Derivatives through Copper-Catalyzed Intramolecular N-Arylation. Beilstein J. Org. Chem. 2013, 9, 2463–2469.
25.Lei Zhang,# Fei Zhao,# Mingyue Zheng, Hong Liu.* Rapid and Selective Access to Three Distinct Sets of Indole-Based Heterocycles from a Single Set of Ugi-Adducts under Microwave Heating. Chem. Commun. 2013, 49, 2894–2896.
主持科研项目：
1.主持国家自然科学基金青年项目: 选择性 α1A 肾上腺素受体拮抗剂的设计、合成及抗前列腺增生药理活性研究, 21602022, 2018.01-2020.12。
2.主持四川省科技厅应用基础面上项目: 用于治疗良性前列腺增生的选择性 α1A 肾上腺素受体拮抗剂的研究, 2018JY0345, 2018.07-2021.06。
3.主持浙江省自然科学基金探索项目: 铑催化 C-H 活化对炔键的官能团化合成吲哚类化合物及其初步抗肿瘤药理活性研究, LY21B020003, 2021.01-2023.12。
4.主持新药研究国家重点实验室(中科院上海药物研究所)开放课题项目, SIMM2105KF-09, 2021.05-2022.05。
5.主持药食同源植物资源开发四川省高校重点实验室开放基金项目, 10Y201711, 2017.7-2019.12。
6.主持抗生素研究与再评价四川省重点实验室开放基金项目, 3-磺酰基取代的吲哚类化合物构建方法及抗菌活性研究, ARRLKF15-01, 2016.1-2017.12。
7.主持成都大学引进人才科研启动基金, 过渡金属催化的杂环构建方法学研究, 2081915037, 2015.07-2020.06。
8.主持四川省千人计划创新人才项目, 2018.07-2021.06。
9.主持成都市蓉漂计划创新人才项目, 2018.10-2021.09。
10.主持成都市成华区英才计划领军人才项目, 2018.10-2021.09。
11.主持欧盟玛丽居里学者项目: Bio- & Photo-Catalytic Methods for the Construction of Enantiomerically Pure C-S Bonds in Thiols and Sulphides, 06/2021-05/2023。
授权专利：
1.赵飞, 乔进, 张小宁, 卢杨斌, 龚鑫, 刘思宇, 具有5-羟基呋喃-2(5H)-酮骨架的化合物及其制备方法, 授权专利号: ZL 202111211587.7
2.赵飞, 乔进, 张小宁, 卢杨斌, 龚鑫, 刘思宇, 一种具有呋喃-2(5H)-酮骨架的化合物及其制备方法, 授权专利号: ZL202111210020.8
3.赵飞, 刘思宇, 乔进, 张小宁, 卢杨斌, 龚鑫, 戴龙, 芦世尧, 一种炔基化咪唑并[1,5-a]吲哚化合物及制备方法, 授权专利号: ZL202110778807.8
4.柳红，谢欣，孙海丰，李静，赵飞，陈颖，栗增，周宇，蒋华良，陈凯先，一种六氢二苯并[a,g]喹嗪类化合物的药物用途，授权专利号: ZL201310161512.1
5.柳红，王逸平，赵飞，赵晶，王江，席聪，吴成林，沈昊，韩旭，蒋华良，陈凯先，苯基[a]吲哚[2,3-g]并喹嗪类化合物，其制备方法，药物组合物及其应用，授权专利号: ZL201610192571.9
获奖：
发明项目《一种六氢二苯并[a,g]喹嗪类化合物的药物用途》获得第三十三届上海市优秀发明选拔赛优秀发明银奖(第五完成人)。
蜀ICP备10000600号
