过渡金属催化C-H官能团化及其新结构产物生物活性研究。

1. Wenbo Ma*, Yuqiang Tan, Yang Wang, Zhiyi Li, Zheyu Li, Linghui Gu*, Ruhuai Mei, and An Cheng “Hydroxyl-Directed Ruthenium-Catalyzed peri-Selective C–H Acylmethylation and Annulation of Naphthols with Sulfoxonium Ylides”, Org. Lett. 2021, 16, 6200-6205. (IF: 6.1)
2. Linghui Gu, Xinyue Fang, Zhengyun Weng, Jiafu Lin, Meicui He, Wenbo Ma*, “PIDA-Promoted Selective C5 C-H Selenylations of Indolines via Weak Interactions”, Adv. Synth. Catal., 2019, 361, 4998– 5004. (IF: 5.8)
3. Meicui He, Linghui Gu+, Yuqiang Tan, Yang Wang, Yuchi Wang, Chunran Zhang, Wenbo Ma* “Palladium-Catalyzed Distal C-H Selenylation of 2-Aryl Acetamides with Diselenides and Selenyl Chlorides”, Adv. Synth. Catal. 2020, 362, 5708– 5715. (IF: 5.8)
4. Wenbo Ma*, Yang Wang, Bo Li, Yunhao Zhou, Yue Xu, Yanan Sun, Linghui Gu*, An Cheng, “Rhodium-Catalyzed Oxidative Coupling of Potassium Vinyltrifluoroborate with Arenes: A Direct Access to Functionalized Styrene Derivatives”, Adv. Synth. Catal. 2022, 364, 3881– 3887. (IF: 5.8)
5. Linghui Gu, Xinyue Fang, Zhengyun Weng, Yupin Song, Wenbo Ma*, “Ligand- Free Palladium(II)‐Catalyzed ortho-C-H Chalcogenations of N-Arylsulfonamide via Weak Coordination”, Eur. J. Org. Chem. 2019, 1825–1829. (IF: 3.3)
6. Linghui Gu, Yang Wang, Zemin Cheng, Yanan Sun, Xin Gong, Zheyu Li, Wenbo Ma*, “Brønsted Acid Promoted N-Dealkylation of N-Alkyl(sulfon) amides”, ChemistrySelect , 2021, 6, 8839 –8842. (IF: 2.3)
7. Feng Xiong, Bo Li, Chenrui Yang, Liang Zou, Wenbo Ma, Linghui Gu*, Ruhuai Mei*, Lutz Ackermann*, “Copper-mediated oxidative C−H/ N−H activations with alkynes by removable hydrazides”, Beilstein J. Org. Chem. 2021, 17, 1591–1599. (IF: 2.5)
8. Shi-Lu Zheng, Yun-Xiang Zou, Zhong Wen, Jia-Fu Lin, Ling-Hui Gu*, Long Chen*, “Y(OTf )3-catalyzed phosphorylation of 2H-chromene hemiacetals with P(O)–H compounds to 2-phosphorylated 2H-chromenes”, Org. Biomol. Chem., 2021, 19, 6812–6816. (IF: 3.9)

纵向课题：
1.主持四川省科技厅应用基础项目:《过渡金属钌催化依布硒啉衍生物的绿色合成及其在抗菌药物中的应用》，2022NSFSC0623，2022-2023。
2.主持抗生素研究与再评价四川省重点实验室开放课题项目：《铜催化新型磺胺芳基硒醚类化合物合成新方法及其抗肿瘤活性研究》，ARRLKF17-04 ，2017-2020。
3.参与四川省科技厅应用基础项目:《膦酰基取代杂环化合物的不对称催化构建及生物活性筛选》，2022NSFSC0625，2022-2023。
4.参与四川省科技厅应用基础项目:《锰催化氮杂䓬类化合物的合成及抗菌活性筛选》，2018JY0247，2018-2020。
授权专利：
1. 一种加强的乙酰苯胺类化合物的制备方法。2019，中国专利ZL201710482392.3
2. 硒/硫化磺酰芳胺类化合物及其硒/硫化方法。2021，中国专利ZL201811332588.5