师资队伍

李俊龙

职称:二级教授

最高学历毕业院校及专业:四川大学 药物化学

所属学科:药物化学

电子邮件:lijunlong709@hotmail.com

个人简历

研究方向

代表性论著

教学科研项目及获奖

职称 二级教授 最高学历毕业院校及专业 四川大学 药物化学
所属学科 药物化学 电子邮箱 lijunlong709@hotmail.com
研究方向 主要研究方向为有机合成新方法开发、手性药物及抗感染药物合成。 发表论文 1.Q.-Z. Li,† R. Zeng,† P.-S. Xu, Xn.-H. Jin, C. Xie, Q.-C. Yang, X. Zhang, J.-L. Li,* Direct Acylation of Unactivated Alkyl Halides with Aldehydes through N-Heterocyclic Carbene Organocatalysis. Angew. Chem. Int. Ed., 2023, e202309572.<br>
2.Q.-Z. Li,† Y.-Q. Liu,† X.-X. K, W.-L. Zou, T. Qi, P. Xiang, J.-D. Xing, X. Zhang, J.-L. Li,* Oxidative Radical NHC Catalysis: Divergent Difunctionalization of Olefins through Intermolecular Hydrogen Atom Transfer. Angew. Chem. Int. Ed., 2022, 61, e202207824.<br>
3.Q.-Z. Li,† R. Zeng,† Y. Fan, Y.-Q. Liu, T. Qi, X. Zhang, J.-L. Li,* Remote C(sp3)-H Acylation of Amides and Cascade Cyclization via N-Heterocyclic Carbene Organocatalysis. Angew. Chem. Int. Ed., 2022, 61, e202116629. (VIP Paper).<br>
4.J.-L. Li,† Y.-Q. Liu,† W.-L. Zou, R. Zeng, X. Zhang, Y. Liu, B. Han,* Y. He, H.-J. Leng, Q.-Z. Li,* Radical Acylfluoroalkylation of Olefins through N-Heterocyclic Carbene Organocatalysis. Angew. Chem. Int. Ed., 2020, 59, 1863.<br>
5.B. Han,† X.-H. He,† Y.-Q. Liu, G. He, C. Peng, J.-L. Li,* Asymmetric Organocatalysis: An Enabling Technology for Medicinal Chemistry. Chem. Soc. Rev., 2021, 50, 1522.<br>
6.H.-P. Li,† X.-H. He,† C. Peng,* J.-L. Li,* B. Han,* A Straightforward Access to Trifluoromethylated Natural Products through Late-Stage Functionalization. Nat. Prod. Rep., 2023, 40, 988.<br>
7.H. Huang, Q.-S. Dai, H.-J. Leng, Q.-Z. Li, S.-L. Yang, Y.-M. Tao, X. Zhang, T. Qi, J.-L. Li,* Suzuki-Type Cross-Coupling of Alkyl Trifluoroborates with Acid Fluoride Enabled by NHC/Photoredox Dual Catalysis. Chem. Sci., 2022, 13, 2584.<br>
8.Q. Li, L. Zhou, X.-D. Shen, K.-C. Yang, X. Zhang, Q.-S. Dai, H.-J. Leng, Q.-Z. Li, J.-L. Li,* Stereoselective Construction of Halogenated Quaternary Carbon Centers by Brønsted Base Catalyzed [4+2] Cycloaddition of α-Haloaldehydes. Angew. Chem. Int. Ed., 2018, 57, 1913.<br>
9.Q.-Z. Li,† Y.-L Guan,† Q.-W. Huang, T. Qi, P. Xiang, X. Zhang, H.-J. Leng, J.-L. Li,* Temperature-Controlled Divergent Asymmetric Synthesis of IndoleBased MediumSized Heterocycles through Palladium Catalysis, ACS Catal., 2023, 13, 1164.<br>
10.Q.-W. Huang, T. Qi, Y. Liu, X. Zhang, Q.-Z. Li, C. Gou, Y.-M. Tao, H.-J. Leng, J.-L. Li,* Lewis Acid/Brønsted Base-Assisted Palladium Catalysis: Stereoselective Construction of Skeletally Diverse Spiro-Ketolactams from Vinylethylene Carbonates. ACS Catal., 2021, 11, 10148.<br>
11.R. Zeng, J.-L. Li,* X. Zhang, Y.-Q. Liu, Z.-Q. Jia, H.-J. Leng, Q.-W. Huang, Y. Liu, Q.-Z. Li,* Diastereoselective Construction of 6,8-Dioxabicyclo[3.2.1]octane Frameworks from Vinylethylene Carbonates via Palladium-Organo Relay Catalysis. ACS Catal., 2019, 9, 8256.<br>
12.Q.-Z. Li, X. Zhang, K. Xie, Q.-S. Dai, R. Zeng, Y.-Q. Liu, Z.-Q. Jia, X. Feng, J.-L. Li,* Diastereodivergent Synthesis of Cyclopropanes via On-Water [2+1] Annulations of Diazo Compounds with Electron-Deficient Alkenes. Green Chem., 2019, 21, 2375.<br>
13.J.-L. Li, B. Sahoo, C.-G. Daniliuc, F. Glorius*, Conjugate Umpolung of β,β-Disubstituted Enals via N-Heterocyclic Carbene and Brønsted Acid Dual Catalysis: Facile Construction of Contiguous Quaternary Stereocenters, Angew. Chem. Int. Ed., 2014, 53, 10515.<br>
14.J.-L. Li, C.-Z. Yue, P.-Q. Chen, Y.-C. Xiao, Y.-C. Chen*, Remote Enantioselective Fri -Activation, Angew. Chem. Int. Ed., 2014, 53, 5449.<br>
15.J.-L. Li, B. Sahoo, C.-G. Daniliuc, F. Glorius,* Conjugate Umpolung of β,β-Disubstituted Enals by Dual Catalysis with an N-Heterocyclic Carbene and a Brønsted Acid: Facile Construction of Contiguous Quaternary Stereocenters. Angew. Chem. Int. Ed., 2014, 53, 10515.
16.J.-L. Li, T.-Y. Liu, Y.-C. Chen,* Aminocatalytic Asymmetric Diels–Alder Reactions via HOMO Activation. Acc. Chem. Res., 2012, 45, 1491.<br>
17.J.-L. Li, T.-R. Kang, S.-L. Zhou, R. Li, L. Wu, Y.-C. Chen*, Organocatalytic Asymmetric Inverse Electron Demand Diels-Alder Reaction of Electron Deficient Dienes and Crotonaldehyde, Angew. Chem. Int. Ed., 2010, 49, 6418.<br>
教学科研成果 一、教学科研项目<br>
1.国家自然科学基金面上项目,2023/01-2026/12,主持;<br>
2.国家自然科学基金面上项目,2019/01-2022/12,主持;<br>
3.国家自然科学基金青年基金项目,2016/01-2018/12,主持;<br>
4.四川省自然科学基金创新研究群体项目,2023/01-2025/12,主持;<br>
5.四川省杰出青年基金,2017/03-2019/12,主持;<br>
6.成都大学研究生人才培养教学改革重点项目,2021/01-2023/12,主持。<br>
二、获奖<br>
1.2023 “Asian Core Program Lectureship Award”国际学术奖<br>
2.2021 中华医学会青年科技奖<br>
3.2021 四川省高等教育教学成果奖二等奖<br>
4.2019 四川省科学技术进步一等奖<br>
5.2019 Thieme Chemistry Journals Award国际学术奖<br>
6.2011 教育部博士研究生学术新人奖<br>

李俊龙,博士研究生,二级教授,成都大学药学院副院长,四川抗菌素工业研究所副所长,四川省抗感染药物创制工程研究中心副主任,《中国抗生素杂志》副主编,《国外抗生素分册》副主编,《Chinese Chemical Letters》青年编委,《Green Synthesis & Catalysis》青年编委,四川省侨联特聘专家委员会专家,四川省药学会药学教育专委会委员,四川省科技青年联合会理事,成都市科技联合会副主席。

求学经历:

2013年于四川大学华西药学院获得博士学位,师从陈应春教授;

2013-2015年,德国明斯特大学,博士后,合作教授Frank Glorius

获奖或荣誉称号

德国洪堡学者、四川省学术和技术带头人、四川省天府峨眉计划获得者、四川省杰青、成都市“蓉漂”计划专家;获四川省科技进步一等奖、中华医学会青年科技奖,

2019年度 “Thieme Chemistry Journals Award”国际学术奖,2023年度“Asian Core Program Lectureship Award”国际学术奖 ,教育部“博士学术新人奖”,入选2022年全球前2%科学家榜单。

主要研究方向为有机合成新方法开发、手性药物及抗感染药物合成。

1.Q.-Z. Li,† R. Zeng,† P.-S. Xu, Xn.-H. Jin, C. Xie, Q.-C. Yang, X. Zhang, J.-L. Li,* Direct Acylation of Unactivated Alkyl Halides with Aldehydes through N-Heterocyclic Carbene Organocatalysis. Angew. Chem. Int. Ed., 2023, e202309572.
2.Q.-Z. Li,† Y.-Q. Liu,† X.-X. K, W.-L. Zou, T. Qi, P. Xiang, J.-D. Xing, X. Zhang, J.-L. Li,* Oxidative Radical NHC Catalysis: Divergent Difunctionalization of Olefins through Intermolecular Hydrogen Atom Transfer. Angew. Chem. Int. Ed., 2022, 61, e202207824.
3.Q.-Z. Li,† R. Zeng,† Y. Fan, Y.-Q. Liu, T. Qi, X. Zhang, J.-L. Li,* Remote C(sp3)-H Acylation of Amides and Cascade Cyclization via N-Heterocyclic Carbene Organocatalysis. Angew. Chem. Int. Ed., 2022, 61, e202116629. (VIP Paper).
4.J.-L. Li,† Y.-Q. Liu,† W.-L. Zou, R. Zeng, X. Zhang, Y. Liu, B. Han,* Y. He, H.-J. Leng, Q.-Z. Li,* Radical Acylfluoroalkylation of Olefins through N-Heterocyclic Carbene Organocatalysis. Angew. Chem. Int. Ed., 2020, 59, 1863.
5.B. Han,† X.-H. He,† Y.-Q. Liu, G. He, C. Peng, J.-L. Li,* Asymmetric Organocatalysis: An Enabling Technology for Medicinal Chemistry. Chem. Soc. Rev., 2021, 50, 1522.
6.H.-P. Li,† X.-H. He,† C. Peng,* J.-L. Li,* B. Han,* A Straightforward Access to Trifluoromethylated Natural Products through Late-Stage Functionalization. Nat. Prod. Rep., 2023, 40, 988.
7.H. Huang, Q.-S. Dai, H.-J. Leng, Q.-Z. Li, S.-L. Yang, Y.-M. Tao, X. Zhang, T. Qi, J.-L. Li,* Suzuki-Type Cross-Coupling of Alkyl Trifluoroborates with Acid Fluoride Enabled by NHC/Photoredox Dual Catalysis. Chem. Sci., 2022, 13, 2584.
8.Q. Li, L. Zhou, X.-D. Shen, K.-C. Yang, X. Zhang, Q.-S. Dai, H.-J. Leng, Q.-Z. Li, J.-L. Li,* Stereoselective Construction of Halogenated Quaternary Carbon Centers by Brønsted Base Catalyzed [4+2] Cycloaddition of α-Haloaldehydes. Angew. Chem. Int. Ed., 2018, 57, 1913.
9.Q.-Z. Li,† Y.-L Guan,† Q.-W. Huang, T. Qi, P. Xiang, X. Zhang, H.-J. Leng, J.-L. Li,* Temperature-Controlled Divergent Asymmetric Synthesis of IndoleBased MediumSized Heterocycles through Palladium Catalysis, ACS Catal., 2023, 13, 1164.
10.Q.-W. Huang, T. Qi, Y. Liu, X. Zhang, Q.-Z. Li, C. Gou, Y.-M. Tao, H.-J. Leng, J.-L. Li,* Lewis Acid/Brønsted Base-Assisted Palladium Catalysis: Stereoselective Construction of Skeletally Diverse Spiro-Ketolactams from Vinylethylene Carbonates. ACS Catal., 2021, 11, 10148.
11.R. Zeng, J.-L. Li,* X. Zhang, Y.-Q. Liu, Z.-Q. Jia, H.-J. Leng, Q.-W. Huang, Y. Liu, Q.-Z. Li,* Diastereoselective Construction of 6,8-Dioxabicyclo[3.2.1]octane Frameworks from Vinylethylene Carbonates via Palladium-Organo Relay Catalysis. ACS Catal., 2019, 9, 8256.
12.Q.-Z. Li, X. Zhang, K. Xie, Q.-S. Dai, R. Zeng, Y.-Q. Liu, Z.-Q. Jia, X. Feng, J.-L. Li,* Diastereodivergent Synthesis of Cyclopropanes via On-Water [2+1] Annulations of Diazo Compounds with Electron-Deficient Alkenes. Green Chem., 2019, 21, 2375.
13.J.-L. Li, B. Sahoo, C.-G. Daniliuc, F. Glorius*, Conjugate Umpolung of β,β-Disubstituted Enals via N-Heterocyclic Carbene and Brønsted Acid Dual Catalysis: Facile Construction of Contiguous Quaternary Stereocenters, Angew. Chem. Int. Ed., 2014, 53, 10515.
14.J.-L. Li, C.-Z. Yue, P.-Q. Chen, Y.-C. Xiao, Y.-C. Chen*, Remote Enantioselective Fri -Activation, Angew. Chem. Int. Ed., 2014, 53, 5449.
15.J.-L. Li, B. Sahoo, C.-G. Daniliuc, F. Glorius,* Conjugate Umpolung of β,β-Disubstituted Enals by Dual Catalysis with an N-Heterocyclic Carbene and a Brønsted Acid: Facile Construction of Contiguous Quaternary Stereocenters. Angew. Chem. Int. Ed., 2014, 53, 10515. 16.J.-L. Li, T.-Y. Liu, Y.-C. Chen,* Aminocatalytic Asymmetric Diels–Alder Reactions via HOMO Activation. Acc. Chem. Res., 2012, 45, 1491.
17.J.-L. Li, T.-R. Kang, S.-L. Zhou, R. Li, L. Wu, Y.-C. Chen*, Organocatalytic Asymmetric Inverse Electron Demand Diels-Alder Reaction of Electron Deficient Dienes and Crotonaldehyde, Angew. Chem. Int. Ed., 2010, 49, 6418.

一、教学科研项目
1.国家自然科学基金面上项目,2023/01-2026/12,主持;
2.国家自然科学基金面上项目,2019/01-2022/12,主持;
3.国家自然科学基金青年基金项目,2016/01-2018/12,主持;
4.四川省自然科学基金创新研究群体项目,2023/01-2025/12,主持;
5.四川省杰出青年基金,2017/03-2019/12,主持;
6.成都大学研究生人才培养教学改革重点项目,2021/01-2023/12,主持。
二、获奖
1.2023 “Asian Core Program Lectureship Award”国际学术奖
2.2021 中华医学会青年科技奖
3.2021 四川省高等教育教学成果奖二等奖
4.2019 四川省科学技术进步一等奖
5.2019 Thieme Chemistry Journals Award国际学术奖
6.2011 教育部博士研究生学术新人奖