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药剂学

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谢佳妮

讲师

所属学科:药剂学 电子邮件:xiejiani@cdu.edu.cn

最高学历毕业院校及专业:中国科学院高能物理研究所

个人简介

谢佳妮博士特聘研究员硕士生导师

学术兼职:成都大学学报(自然科学版)青年编委

学术经历:中国科学院高能物理研究所(硕博连读)

获奖或荣誉称号:四川省“卫生健康英才计划”中青年骨干人才,成都大学青椒计划 “青年科研新锐”。

研究方向

新型纳米药物的设计制备及其在医学放射防护中的应用。

代表性论著

1. Liu, Z.#; Liu, X. #; Li, Z. #; Xie, J. #(共同第一作者); Gao, K.; Pei, Y.; Gu, Z.*; Peng, X.*, Fullerene for Reducing Acute Radiation Dermatitis in Patients Undergoing Radiotherapy for Head and Neck Cancer: A Phase II, Double-Blind, Randomized Controlled Trial. Journal of Clinical Oncology 2026, JCO2502264. (IF= 44.7)
2. Xie, J.; Zhou, Y.; Wu, Y.; Zhang, Z; Lv, N.; Li, W.; Zhao, M.; Wang, C; Yong, Y.*; Zou, L.*; Gu, Z.* Fullerenes and Their Derivatives for Mitigating Oxidative Stress Disorders: Anti-Oxidative Mechanistic Insights, Anti-Oxidative Damage Applications and Translational Progress. Carbon 2026, 121964. (IF= 12.7)
3. Xie, J.*; Dong, R.; Zhang, T.; Guo, F.; Li, H.; Chen, X.; Wu, Y.; Zhang, X.; Yong, Y.; Gu, Z.* Natural dietary ROS scavenger-based nanomaterials for ROS-related chronic disease prevention and treatment. Chemical Engineering Journal 2024, 490, 151756. (IF= 12.5)
4. Liu, Y.; Wang, C.; Liu, R.; Zhao, M.; Ding, X.; Zhang, T.; He, R.; Zhu, S.; Dong, X.; Xie, J.*; Gu, Z.*; Zhao, Y.*, Adhesive Ergothioneine Hyaluronate Gel Protects against Radiation Gastroenteritis by Alleviating Apoptosis, Inflammation, and Gut Microbiota Dysbiosis. ACS Applied Materials & Interfaces 2023, 15(16):19833-19846. (IF=7.8)
5. Xie, J.; Zhao, M.; Wang, C.; Yong, Y.; Gu, Z.* Recent advances in understanding the effects of nanomaterials on gut microbiota. Chemical Engineering Journal 2022, 435, 134976. (IF=12.5)
6. Xie, J.; Zhao, M.; Wang, C.; Zhu, S.; Niu, W.; Yong, Y.; Zhao, L.; Gu, Z.* External use of Nano-graphdiyne hydrogel for skin radioprotection via both physically shielding of Low-energy X-ray and chemically scavenging of Broad-spectrum free radicals. Chemical Engineering Journal 2022, 430, 132866. (IF= 12.5)
7. Wang, C.; Zhao, M.; Xie, J.*; Ji, C.; Leng, Z.; Gu, Z.* Fullerenol@nano-montmorillonite nanocomposite as an efficient radioprotective agent for ameliorating radioactive duodenal injury. Chemical Engineering Journal 2022, 427, 131725. (IF=12.5)
8. Xie, J.; Zhao, M.; Wang, C.; Yong, Y.; Gu, Z.*; Zhao, Y.* Rational Design of Nanomaterials for Various Radiation-Induced Diseases Prevention and Treatment. Advanced Healthcare Materials 2021, 10 (6), e2001615. (IF= 11.0)
9. Zhao, M.; Wang, C.; Xie, J.*; Ji, C.; Gu, Z.* Eco-friendly and scalable synthesis of fullerenols with high free radical scavenging ability for skin radioprotection. Small 2021, 17(37), 2102035. (IF= 11.8)
10. Xie, J.; Wang, C.; Wang, N.; Zhu, S.; Mei, L.; Zhang, X.; Yong, Y.; Li, L.; Chen, C.; Huang, C.*; Gu, Z.*; Li, Y.; Zhao, Y. Graphdiyne nanoradioprotector with efficient free radical scavenging ability for mitigating radiation-induced gastrointestinal tract damage. Biomaterials 2020, 244, 119940. (IF= 13.6)
11. Wang, C.; Xie, J.(共同第一作者); Dong, X.; Mei, L.; Zhao, M.; Leng, Z.; Hu, H.; Li, L.; Gu, Z.*; Zhao, Y. Clinically Approved Carbon Nanoparticles with Oral Administration for Intestinal Radioprotection via Protecting the Small Intestinal Crypt Stem Cells and Maintaining the Balance of Intestinal Flora. Small 2020, 16(16), 1906915. (IF=11.8)
12. Xie, J.; Gong, L.; Zhu, S.; Yuan, Y.; Gu, Z.*; Zhao, Y. Emerging Strategies of Nanomaterial-Mediated Tumor Radiosensitization. Advanced Materials 2019, 31(3), e1802244. (IF= 29.1)
13. Xie, J.; Wang, N.; Dong, X.; Wang, C.; Du, Z.; Mei, L.; Yong, Y.; Huang, C.*; Li, Y.; Gu, Z.*; Zhao. Y. Graphdiyne Nanoparticles with High Free Radical Scavenging Activity for Radiation Protection. ACS Applied Materials & Interfaces 2019, 11(3), 2579-2590. (IF=7.8)
14. Xie, J.; Wang, C.; Zhao, F.*; Gu, Z.*; Zhao, Y.* Application of Multifunctional Nanomaterials in Radioprotection of Healthy Tissues. Advanced Healthcare Materials 2018, 7(20), 1800421. (IF= 11.0)

教学科研项目及获奖

奖励:
1.2023年获四川省“卫生健康英才计划中青年骨干人才”称号;
2.2020年入选成都大学青椒计划,获“青年科研新锐”称号;
3.2019年获“北京市优秀博士毕业生”;
4.2018年获“博士研究生国家奖学金”。
代表性科研项目:
1.国家自然科学基金青年科学基金项目,52003031,2021-01至2023-12,主持。
2.四川省自然科学基金青年基金项目,2023NSFSC1452,2023-01至2024-12,主持。
3.成都市重点研发项目—技术创新研发项目,2024-YF05-00780-SN,2025-06至2026-05,主持。
4.四川省重点实验室开放课题,NMRSKL2601,2026-07-01至2028-06-30,主持。
5.教育部重点实验室开放基金项目,MZY2208,2022-09至2024-12,主持。
6.成都大学高层次人才计划培育项目,2081923085,2023-01至2027-12,主持。
7.成都大学校人才工程科研启动项目,2081920047,2019-09至2022-09,主持。
8.国家重点研发计划/国家科技重大专项,D23025,2023-01至2027-12,参与。
9.国家自然科学基金联合基金项目,U1932112,2020-01至2022-12,参与。
10.国家自然科学基金面上项目,51772292,2018-01至2021-12,参与。
授权专利:
1. 谷战军,谢佳妮,董兴华,赵宇亮。石墨炔纳米材料作为自由基清除剂及辐射防护剂的新用途。中国发明专利,ZL201810163407.4。
2. 谷战军,谢佳妮,赵宇亮。一种水凝胶材料及其制备方法和用途。中国发明专利,ZL201910526350.4。
3. 雍媛,刘佳杰,刘巧沐,谢佳妮。一种靶向线粒体的人工代谢酶及其制备方法与应用。中国发明专利,ZL2024118172044。