抗感染药物的研究与开发

1. Baowen Qi, Ling Zhong, Jun He, Hongjia Zhang, Fengqiong Li, Ting Wang, Jing Zou,Yao-Xin Lin, Chengchen Zhang, Xiaoqiang Guo, Rui Li, and Jianyou Shi, Discovery of Inhibitors of Aurora/PLK Targets as Anticancer Agents[J]. Journal of Medicinal Chemistry. 2019, 62, 7697−7707
2. Xiaofei Du , Haiyan Jiang , Xiaoqiang Guo , Lianmei Chen *, Tairan Kang. Synthesis of ferrocene/chitosan-AgNPs films and application in plasmonic color-switching and antimicrobial materials[J]. Reactive and Functional Polymers. 2021,169, 105061
3. Ren Kong , Guangbo Yang , Rui Xue  , Ming Liu, Feng Wang , Jianping Hu , Xiaoqiang Guo, Shan Chang.COVID-19 Docking Server: a meta server for docking small molecules, peptides and antibodies against potential targets of COVID-19 [J].Bioinformatics.2020,36,5109-5111
4. Yucheng Zhang, Jiahao Liu, Hongxia Xing, Yaxuan Huang, Qian Yao, Tairan Kang, Xiaoqiang Guo, Total synthesis of eucryphin and its glycosylation derivatives[J]. Tetrahedron，2022,122,132949
5. Yucheng Zhang, Jiahao Liu, Qian Yao, Hong Deng , Caimei Yao, Tairan Kang, Xiaoqiang Guo. Eucryphin analog’s total synthesis, anti-inflammatory activity for DNFB-induced contact hypersensitivity and structure-activity relationship[J]. Journal of Molecular Structure.2023, 1293,136215.
6. Xingyu Chen, Caimei Yao, Jiahao Liu, Jintao Liu, Jingmei Fang, Hong Deng, Qian Yao, Tairan Kang* and Xiaoqiang Guo. Basic helix-loop-helix (bHLH) gene family in rye (Secale cereale L.): genome-wide identification, phylogeny, evolutionary expansion and expression analyses[J]. BMC Genomics. 2025, 25,67
7. Xingyu Chen, Wenbo Ma, Tairan Kang, Peng Sun, Xiaoqiang Guo.Benzoisoxazoles as Privileged Scaffolds in the Design and Synthesis of N-containing Molecules: A Recent Update[J].Eur. J. Org. Chem. 2025,28,e202401021
8. Dongyan Duan, Hua Xie, Jiayi Jiang, Ping Yang, Zhiyuan Guo, Xiaoqiang Guo , Xingyu Chen, Qian Yao.Permeability-Enhancing and Protective Effect on Small Intestine of Punicic Acid in Different Forms and Their Nan With Low Toxicity[J].International Journal of Nanomedicine. 2025,20,1579–1596
9. Meichen Li , Yi Peng , Qingqing Xiao , Siyi Chen , Chunjie Zhang, Hongyu Chen, Yue Zhao, Shan Chang , Lu Qiu , Lele Zhang , Xiaoqiang Guo, Qiang Fu.Pharmacological inhibition of PGK1 by genipin reduces inflammation and oxidative damage in osteoarthritis[J].Phytomedicine.2026,150,157729
10. Duan D, Xie H, Jiang J, Yang P, Guo Z, Guo X, Chen X, Yao Q. Permeability-Enhancing and Protective Effect on Small Intestine of Punicic Acid in Different Forms and Their Nanoemulsions With Low Toxicity[J]. Int J Nanomedicine. 2025,20,1579-1596

主持国家级、省部级科研项目 10 余项；发表科研论文 60 余篇；主编或参编著作 5 部；授权发明专利 5 件；科研成果获四川省政府科技进步二等奖 1 项、三等奖 2 项。主持国家虚拟仿真实验教学项目 1 项和国家级一流本科课程 1 门，获四川省高等教育教学成果奖二等奖 2 项。
一、科研项目
1. 四川省重点研发项目，20万元，202201-202312，主持；
2. 四川省应用基础研究项目，10万元，201709-201909，主持；
3. 广东省重点领域研发计划，250万元，202206-202602，主持；
4. 成都市技术创新研发项目，202206-202306，主持；
5. 成都市重点研发支撑计划，500万元，202605-202904，主持。
二、授权专利
1. 发明专利：落新妇苷衍生物及其制备方法，专利号：ZL201610459223.3，第一发明人；
2. 发明专利：一种落新妇苷氨基吡啶类衍生物靶向前药及其制备方法和应用，专利号：ZL201910160853.4，第一发明人；
3. 发明专利：苯甲酸雌二醇与缩宫素长效混悬注射液的制备方法，专利号：ZL202110290222.1，第一发明人；
4. 发明专利：一种二氧化氯缓释剂、制备工艺及应用，专利号：ZL202310203232.6，第一发明人；
5. 发明专利：黄杞叶提取物作为α-葡萄糖苷酶抑制剂的应用，专利号ZL202111524974.6，第一发明人。