绿色药物合成方法学研究；靶向小分子药物设计、合成研究。

1.Wenbo Ma*, Yang Wang, Bo Li, Yunhao Zhou, Yue Xu, Yanan Sun and Linghui Gu*, An Cheng, Rhodium-Catalyzed Oxidative Coupling of Potassium Vinyltrifluoroborate with Arenes: An Efficient Access to Functionlized Styrene Derivatives, Adv. Synth. Catal., 2022, 364, 3881-3887.
2.Wenbo Ma,* Yunhao Zhou, Yang Wang, Bo Li, Tao Zheng, Zemin Cheng, and Ruhuai Mei, Palladium-Catalyzed Remote δ-C–H Selenylation of Arylethylamide and Alkenylethylamide Derivatives , Adv. Synth. Catal. 2022, 364, 3544– 3550.
3.Bo Li, Yunhao Zhou, Yanan Sun, Feng Xiong, Linghui Gu, Wenbo Ma * and Ruhuai Mei*， Electrochemical selenium–π–acid promoted hydration of alkynyl phosphonates, Chem. Commun., 2022, 58, 7566–7569
4.Yao Yu, Yang Wang, Bo Li, Yuqiang Tan, Huan Zhao, Zheyu Li, Chunran Zhang, Wenbo Ma* Ruthenium-Catalyzed Vinylene Carbonate Annulation by C-H/N-H Functionalizations: Step-Economical Access to Indoles, Adv. Synth. Catal. 2022, 364, 838-844.
5.Wenbo Ma*, Yuqiang Tan, Yang Wang, Zhiyi Li, Zheyu Li, Linghui Gu, Ruhuai Mei, and An Cheng, Hydroxyl-Directed Ruthenium-Catalyzed peri-Selective C–H Acyl-methylation and Annulation of Naphthols with Sulfoxonium Ylides, Org. Lett. 2021, 23, 6200-6205.
6.Xinyue Fang, Yuqiang Tan, Linghui Gu Lutz Ackermann, and Wenbo Ma*,“para‐Selective Palladium-Catalyzed C–H Difluoroalkylation by Oxazolidinones Weak Assistance”ChemCatChem, 2021, 13, 1738-1742.
7.Meicui He, Linghui Gu, Yuqiang Tan, Yang Wang, Yuchi Wang, Chunran Zhang and Wenbo Ma* “Palladium-Catalyzed Distal C–H Selenylation of 2-Aryl Acetamides with Diselenides and Selenyl Chlorides” Adv. Synth. Catal. 2020, 362, 5708-5715.
8.Wenbo Ma*, Nikolaos Kaplaneris, Xinyue Fang, Linghui Gu, Ruhuai Mei, Lutz Ackermann*, Chelation-assisted transition metal-catalysed C–H chalcogenylations, Org. Chem. Front., 2020, 7, 1022-1060.
9.Zhengyun Weng, Xinyue Fang, Meicui He, Linghui Gu, Jiafu Lin, Zheyu Li, Wenbo Ma*, Ruthenium Catalyzed C–H Selenylations of Aryl Acetic Amides and Esters via Weak Coordination, Org. Lett. 2019, 21, 6310–6314.
10.Linghui Gu, Xinyue Fang, Zhengyun Weng, Jiafu Lin, Meicui He, Wenbo Ma*, PIDA‐Promoted Selective C 5 C−H Selenylations of Indolines via Weak Interactions , Adv. Synth. Catal., 2019, 361, 4998-5004.
11.Wenbo Ma*, Zhengyun Weng, Torben Rogge, Linghui Gu, Jiafu Lin, Ai Peng, Xiang Luo, Xiaojun Gou, and Lutz Ackermann, “Ruthenium(II)-Catalyzed C-H Chalcogenation of Anilides” Adv. Synth. Catal. 2018, 360, 704–710.
12.Wenbo Ma* Parthasarathy Gandeepan,* Jie Li and Lutz Ackermann* “Recent advances in positional-selective alkenylations by twofold C–H activations”. Org. Chem. Front, 2017, 1435-1467.
13.Wenbo Ma,* Hongbo Dong, Daoxin Wang and Lutz Ackermann* “Late-Stage NSAIDs Diversification by Transition Metal-Catalyzed C–H Alkenylations, Thiolations and Selenylations”. Adv. Synth. Catal. 2017, 359, 966-973 (selected as front cover picture)
14.Wenbo. Ma, Lutz. Ackermann, "Cobalt(II)-Catalyzed Oxidative C−H Alkenylations: Regio- and Site-Selective Access to Isoindolin-1-one" ACS Catal. 2015, 5, 2822–2825. （highly cited paper）
15.Wenbo Ma, Ruhuai Mei, Giammarco Tenti, Lutz Ackermann. Ruthenium(II)-Catalyzed Oxidative C–H Alkenylations of Sulfonic Acids, Sulfonyl Chlorides and Sulfonamides. Chem. Eur. J. 2014, 20, 15248–1525.
16.Wenbo Ma, Lutz Ackermann. "Ruthenium(II)-Catalyzed C-H Alkenylations of Phenols with Removable Directing Groups" Chem. Eur. J. 2013, 19, 13925–13928.
17.Wenbo Ma, Karolina Graczyk, Lutz Ackermann. "Ruthenium-Catalyzed Alkyne Annulations with Substituted 1H-Pyrazoles by C–H/N–H Bond Functionalizations" Org. Lett. 2012, 14, 6318–6321.

纵向课题：
1.主持国家自然科学基金（青年）项目：《过渡金属钌催化C-H键官能化合成（氢化）氮杂卓类化合物及其初步药理活性研究》，21502010， 2016-2018
2.主持四川省科技厅面上项目（应用基础）：《锰催化氮杂䓬类化合物的合成及抗菌活性筛选》，2018JY0247， 2018-2020。
3.主持四川省自然科学基金：《过渡金属催化巴洛沙韦酯(Baloxavir marboxil)类 药物关键母环的合成及应用研究》， 2022NSFSC0620， 2022-2023。
4.成都大学人才引进科研基金，2015-2018， 2018-2023。
横向课题：
1.基于N，O-二氟硼骨架的分子探针在食品领域中的应用。
2.小分子化合物合成技术开发。
授权专利：
1.一种加强的乙酰苯胺类化合物的制备方法。2019, 中国专利, ZL201710482392.3
2. 硒/硫化磺酰芳胺类化合物及其硒、硫化方法。2021, 中国专利, ZL2018 11332588.5
3. 一种含硒化合物及其制备方法与用途。2022, 中国专利, ZL201910365067.8